Observation of sleep apnea in normal subjects using Holter ECG-respiration monitoring system Ken Saito 1 , Naomi Taguchi 1 , Yoshika Miyaike 1 , Keizou Momose 1 , Hiroyoshi Mori 2 1The School of Medical Technology, School of Medicine, Tokushima University 2The Second Department of Internal Medicine, School of Medicine, Tokushima University pp.539-543
Published Date 1988/5/15
DOI https://doi.org/10.11477/mf.1404205257
  • Abstract
  • Look Inside

ECG-respiration recordings were obtained in 15 normal students (all females, ranging age from 19 to 21 years) using Holter ECG-respiration monitoring system. Apnea was noted when flow ceased in the nose for 10 seconds or longer.

Sleep time averaged 422±60 minutes (mean±SD) and 39 episodes of apnea were recognized in 12 subjects during sleep. The mean number of apneic episodes was 2.6 (range 0~12) per night per subject and 10 of 12 subjects (83%) had only one to four episodes. The mean duration of episodes was 13.5 seconds (range 10.2~23.8) and most of the episodes (97%) lasted for less than 20 seconds. There was a moderate positive correlation (r=0.72, p <0.01) between the maximal duration of apnea and the frequency of that in each subject.

The incidence of apnea exhibited a peak at 2-3 a. m. and then gradually reduced.

There was no relationship between the number or duration of apneic episodes and the average autonomic nerve function in each subject but the QTc interval changes tended to precede the frequency of apneic episodes.

These result suggest that the circadian variation of autonomic activity may be responsible for the occurrence of the apneic episodes in normal subjects.

Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院