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A family study of the two cases with arrhythmogenic right ventricular dysplasia with reference to genetic aspects Tadashi Nakanishi 1 , Takeshi Shiroyama 1 , Daisuke Inoue 1 , Masashi Uno 1 , Kooichi Kitamura 1 , Masaaki Kooda 1 , Hiroaki Nakagawa 1 , Masaichi Higami 1 , Masahiro Yoshiga 1 , Hiroki Sugihara 1 , Keizo Furukawa 1 , Jun Asayama 1 , Haruhiko Adachi 1 , Hiroshi Katsume 1 , Hamao Ijichi 1 1The 2nd Department of Internal Medicine, Kyoto Prefectural University of Medicine pp.1009-1014
Published Date 1986/9/15
DOI https://doi.org/10.11477/mf.1404204934
  • Abstract
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Arrhythmogenic right ventricular dysplasia (ARVD) exhibits recurrent VT originating from the right ventri-cle, enlargment and abnormal wall movement of the ventricle in angiogram. About 60 cases of ARVD had been reported up to now. However, there have been no reports which described a clear familial occurrence. We experienced one case of ARVD of 23 year old male whoes uncle also exhibits ARVD. The survey on his family history showed high incidence of sudden death and arrhythmia. As this disease may be a subtype of cardiomyopathy, it should be considered from the aspect of similarity to hereditary mechanism of cardiomyo-pathy. The incidence of this disease is considered to be high among young age group. However in this case, sudden death of older age group is frequent. The uncle (55 year old) who was diagnosed as ARVD has expe-rienced only slight subjective symptom. We cannot deny the possibility of the ARVD as one of the causes of sudden death of aged people. This disease requires broad investigation including the possibility of heredity.


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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