Relationship between coronary artery stenosis and left ventricular global and regional, systolic and diastolic function in coronary artery disease in chronic phase Makio Hayasaka 1 , Kai Tsuiki 1 , Masaki Oguma 1 , Ikuro Ohta 1 , Tetsuji Kaminishi 1 , Seiji Yamaguchi 1 , Shoji Yasui 1 1The First Department of Internal Medicine Yamagata University School of Medicine pp.425-432
Published Date 1986/4/15
DOI https://doi.org/10.11477/mf.1404204856
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Left ventriculography by cardiac catheterization at rest and/or during right atrial pacing was performed in 123 patients with coronary heart disease. Left ventri-cular global systolic, global diastolic, regional systolic and regional diastolic function were measured by ejec-tion fraction (EF), filling ratio at the first-third of the diastole (ER), segmental ejection fraction (SEF, area method) and segmental filling ratio (SFR), respective-ly. The severity of the coronery artery narrowing was estimated by narrowing in diameter and the length of the stenosis (Pujadas' grade). The alteration in left ventricular function as influenced by coronary arterial narrowing was thus studied.

It was observed with respect to global function that FR appeared already abnormal in angina pectoris with three vessel disease without the decrement of EF. To ex-clude the effect due to other coronary stenosis we studied regional function in one vessel disease (left anterior descending artery), in which we observed that SFR was already decreased in mild stenosis (3 of Pujadas' grade) without the decrement of SEF.

Right atrial pacing deteriorated SEF more remarkably in angina pectoris than in myocardial infarction.

It was concluded that 1) left ventricular diastolic function is more sensitive than systolic function in not only global function but also regional function, and that 2) the deterioration of left ventricular regional systolic function during atrial pacing is more remarkable in angina pectoris than in myocardial infarction.

Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.


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