家族性sick sinus syndromeの一家系

A family of familial sick sinus syndrome

　家族性に多発する心ブロックの報告は1901年Mor—quis^1）の報告以来散見されるが，sick sinus syndrome（SSS）に伴う徐脈を呈する家系の報告は少ない。最近，著者らは2世代に4例のSSS患者を有し，さらにこれら症例の5親等の血族2例にペースメーカーが植込まれていた一家系を経験したので，若干の考察を加えて報告する。

A family of familial sick sinus syndrome of adult onset was reported. Case 1 was a 41-year-old man. The electrogram showed sinus bradycardia (HR 35 ;min), sinus arrest with escaped junctional beats and normal PR intervals. Case 2 and 3 (sisters of case 1) were 33 and 50 year-old women. Case 4 (son of case 31 was 25-year-old man. Their ECG showed sinus bradycardia, sinus arrest with escaped junctional beats and normal PR intervals. Physiolo-gical findings, chest X-ray and echocardiogram were normal in all cases. This family was considered familial sick sinus syndrome of adult onset without PR prolongation or other heart disease.