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Varieties in clinical and hemodynamic features of mitral regurgitation due to difference in etiology Hidetsugu Asanoi 1 , Tohru Inasaka 1 , Takashi Kitamura 1 , Akira Fujiki 1 , Shigeo Takata 1 , Takayuki Ikeda 1 , Nobu Hattori 1 1First Department of Internal Medicine, Kanazawa University pp.1113-1118
Published Date 1981/10/15
DOI https://doi.org/10.11477/mf.1404203866
  • Abstract
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The clinical and hemodynamic features were evaluated in 35 patients with mitral regurgitation of various origin. The parameters used were, severity of symptoms (New York Heart Associa-tion : I-IV), grade of regurgitation (Sellers : I-IV), history of heart murmur, and echocardio-graphic measures (the ratio of left atrial dimension to aortic dimension (LAD/Ao), left ventricular end-diastolic dimension (LVDd), and ejection fraction (EF)). The patients with rheumatic heart disease (Rh) were 12, 14 had ruptured chordae tendineae (RCT), and 9 had mitral valve prolapse (MVP).

Compared to Rh patients with functional class III or IV, RCT patients with similar severity showed less increase in LAD/Ao and less decrease in EF. However, the LVDd was not significantly different. Rh patients with regurgitation of grade III or IV showed a marked increase in LAD/Ao but a decrease in EF. In contrast, the EF in RCT patients (except one) remained within normal range. In Rh patients, the longer the histroy of regurgitant murmur, the more the increase in LAD/Ao and the decrease in EF. There was also a tendency for LAD/Ao to in-crease as the history of heart murmur was longer in RCT patients (except four with atrial fibril-lation). All of the MVP patients had regurgita-tion of grade I or II and symptom of class I or II. Most of their hemodynamic data were within normal range.


Copyright © 1981, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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