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A Case of Refractory Vasospastic Angina with Eosinophilia Associated with Bronchial Asthma Eitaro Umehara 1 , Yasuo Komura 1 , Kenji Tamura 1 , Tomonari Kimura 1 , Kazunari Kobayashi 1 1Cardiovascular Center, TAIJU-KAI Foundation Kaisei General Hospital Keyword: 冠攣縮性狭心症 , 好酸球増多 , 副腎皮質ステロイド , vasospastic angina , eosinophilia , corticosteroid pp.93-97
Published Date 2011/1/15
DOI https://doi.org/10.11477/mf.1404101618
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 A-61-year-old woman, who had been diagnosed with vasospastic angina and bronchial asthma was transported to our institution with chest oppression, nausea, vomiting, and dyspnea. She had already taken a calcium antagonist, nitrite, statin and prednisolone (PSL). She had reduced the quantity of PSL 5mg/day to 3mg/day about one month before. Her heart rate fell and she lost consciousness temporarily in the ambulance. Emergent coronary angiography revealed multi-vessel spastic angina. Although Calcium antagonist, nitrite, nicorandil, and inhalation therapy were added, bronchial asthmatic attack and cardiogenic shock recurred. Intravenous administration of methylprednisolone 40mg/6hr followed by oral PSL 20mg/day finally 5mg/day was initiated. She was discharged without any relapse of attacks, and her condition is improving. A high eosinophil count(29%)was found, when she was admitted, and it was 0% when she was discharged. The coronary spasm may have been controlled due to the anti-inframmatory effect of corticosteroid to the hyperresponsiveness of the vascular wall. We report a case of refractory vasospastic angina with eosinophilia associated with bronchial asthma controlled with corticosteroid.


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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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