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要旨●炎症性腸疾患はCrohn病(CD)と潰瘍性大腸炎(UC)があり,ともに内視鏡検査による粘膜面の評価は重要である.カプセル内視鏡検査は低侵襲に粘膜評価を可能とするツールとして実臨床で用いられている.しかしCDには滞留リスクがあり,開通性評価の厳格な判定の必要性が求められる.またCDの病態は炎症と狭窄が混在するため,スコア値の解釈など課題がある.UCに関しては保険適用を十分に加味して患者選択をしなければいけないことや,炎症関連腫瘍のサーベイランスには用いることが困難なこと,さらなる前処置の改良などの課題点が挙げられる.しかし,非侵襲的に粘膜面を観察できるカプセル内視鏡システムは魅力的であり,さらなる発展が期待される.
Inflammatory bowel diseases include Crohn's disease(CD)and ulcerative colitis(UC), both of which require endoscopic evaluation of mucosal surfaces. Capsule endoscopy is conducted as a minimally invasive tool for mucosal evaluation. However, CD is a retention risk, and thus strict patency assessment is required. Additionally, the pathophysiology of CD is a mixture of inflammation and stenosis ; thus, interpreting the score values exhibited issues.
Patient selection regarding UC must be based on insurance coverage, but using it for surveillance of inflammation-related tumors is difficult, and thus further preparation improvement is required. However, the capsule endoscopy system, which enables noninvasive mucosal surface observation, is promising, and its further development is anticipated.
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