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Imaging and Pathology of Early Esophageal Squamous Cell Carcinoma with Poor Prognosis Kenro Kawada 1 , Takashi Ito 2 , Hajime Shinohara 1 , Hiroyuki Shiobara 1 , Katsumasa Saito 1 , Naoto Fujiwara 1 , Akihiro Hoshino 1 , Masanori Tokunaga 1 , Kenichi Ohashi 2 , Yuusuke Kinugasa 1 1Department of Gastrointestinal Surgery, Tokyo Medical and Dental University, Tokyo 2Department of Human Pathology, Tokyo Medical and Dental University, Tokyo Keyword: 食道早期癌 , 食道表在癌 , T1a-MM , 転移 , 予後不良 pp.387-395
Published Date 2022/4/25
DOI https://doi.org/10.11477/mf.1403202690
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 Of 156 cases of early esophageal cancer treated with radical esophagectomy between February 1985 and October 2021, 6 patients had lymph node metastasis, and all of them were pT1a-MM carcinoma and positive for vascular invasion(6 out of 62, 10%).

 Of the 1,171 superficial esophageal cancer cases treated endoscopically at our hospital from December 1989 to October 2021, the frequency of vascular invasion-positive cases was 34, 35 lesions(22%)among 157 lesions in 150 pT1a-MM cancer cases with more than 2 years of follow-up.

 Based on the results of pathology, 6 patients underwent radical surgery, 2 patients underwent radiotherapy, and 1 patient underwent chemoradiotherapy, while out of 141 patients who did not receive additional treatment, 4 patients(3%)subsequently developed metastatic recurrence, and all died of primary disease.

 Overall, 4(2%)of 206 pT1a-MM cancer patients had primary death, 2 of 4 had superficial spreading lesions, 1 was positive for vascular invasion, and 1 was negative for vascular invasion and positive for drop-like infiltration.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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