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Pathological Diagnosis of Scirrhous Gastric Cancer Hiroshi Kawachi 1,2 , Hiroto Noda 2,3 , Kaoru Nakano 1 1Departments of Pathology, the Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 2Department of Pathology, the Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 3Department of Gastroenterology, Nippon Medical School Hospital, Tokyo Keyword: スキルス胃癌 , 4型胃癌 , linitis plastica型胃癌 , 病理診断 pp.770-777
Published Date 2020/5/25
DOI https://doi.org/10.11477/mf.1403202051
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 This article introduced the pathological diagnosis of scirrhous-type gastric cancer, including its historical issues, definition, macroscopic, and histological characteristics, and its relationship with type 4 and linitis plastica-type cancer. Histologically, gastric cancer with prominent fibrotic stroma is regarded as scirrhous-type cancer irrespective of the tumor location, macroscopic type, histological type, and distribution. From a pathological standpoint, scirrhous-type cancer is classified as either linitis plastica type, pyloric stenosis type, type 3 scirrhous cancer, or morphological type 0-IIc scirrhous cancer. However, from a clinical point of view, only linitis plastica and pyloric stenosis types are regarded as scirrhous-type cancer. Notably, type 4 cancer includes nonscirrhous cancer with the migration of isolated or small nested cancer cells in the stroma.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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