The Endoscopic and Pathological Characteristics of Tubular Adenocarcinoma in Comparison between Helicobacter pylori Infected and Eradicated Patients Toshiyuki Wakatsuki 1 , Tomohiko Mannami 1 , Tsukasa Sakaki 1 , Hanako Nagahara 1 , Kazuki Sudou 1 , Yuuhi Sakabayashi 1 , Yasushi Fukumoto 1 , Shin'ichi Furutachi 1 , Shin'ichi Shimizu 1 1Department of Gastroenterology & Hepatology, National Hospital Organization Okayama Medical Center, Okayama, Japan Keyword: H. pylori , H. pylori除菌後胃癌 , 範囲診断 , 被覆 , 腸上皮化生 pp.28-41
Published Date 2020/1/25
DOI https://doi.org/10.11477/mf.1403201923
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 EGC(Early gastric cancer)occurring after successful Helicobacter pylori eradication is difficult to diagnose because of non-neoplastic epithelia covering the periphery of the cancerous surfaces. This might result in an unclear demarcation of the cancer when observed with magnifying endoscopy and narrow-band imaging. EGC that occurs in an area, where the background mucosa contains fundic or pyloric glands, tends to be peripherally covered with non-neoplastic epithelia. Therefore, more careful observation is required when observing EGC located in the areas of fundic or pyloric glands than in the areas of intestinal metaplasia. If an enlarged mucosal structure is found around the tumor margin, it must be suspected that the surface of the cancerous area is covered with non-neoplastic epithelium. Furthermore, it is important to determine whether irregular blood vessels are present in the enlarged mucosal structure.

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