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要旨●当院で経験した75例の自己免疫性胃炎(A型胃炎)の内視鏡所見について述べた.頻度の高い所見として,固着粘液が64%,WGAが56%,残存胃底腺粘膜が45%,過形成性ポリープが39%に認められた.残存胃底腺粘膜の形態は島状〜偽ポリープ状が最も多かった.本症と類似した内視鏡像を呈するopen型萎縮性胃炎との鑑別は予想以上に難しかった.特にHelicobacter pylori除菌後に胃前庭部の幽門腺が改善してきた症例では,胃前庭部の所見のみでは本症との鑑別は困難である.鑑別には胃体部萎縮粘膜部分の平滑さ,微細アレア,点状発赤が少ないこと,境界明瞭な非萎縮残存胃底腺粘膜の形状などの胃体部の所見が参考になることが示唆された.
We analyzed 75 cases of AIG(autoimmune gastritis)diagnosed at Fujieda Municipal General Hospital, Shizuoka Prefecture, Japan. We identified sticky adhered mucus, white globe appearance of lesions, unaffected remnant oxyntic mucosa, and hyperplastic polyps in 64%, 56%, 45%, and 39% of cases, respectively. The unaffected remnant oxyntic mucosa frequently showed island-shaped or pseudo-polyps. Distinguishing AIG from severe atrophic gastritis resembling AIG was unexpectedly difficult. This was especially noted in cases of atrophic gastritis, where the antral mucosa had recovered after Helicobacter pylori eradication. In these cases, the smooth mucosa, fine area, less dotted redness of the atrophic lesion, and clearly-margined unaffected remnant oxyntic mucosa in the gastric body are suggested as useful distinguishing factors.
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