Efficacy of Narrow Band Imaging for Diagnosing Early Gastric Cancer after Helicobacter pylori Eradication Yoshitaka Nawata 1 , Kazuyoshi Yagi 2 , Yuichi Sato 3 1Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan 2Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, Japan 3Department of Internal Medicine, Niigata Prefecture Yoshida Hospital, Tsubame, Japan Keyword: 除菌後発見胃癌 , NBI , 拡大内視鏡 , 中間帯 , 色調逆転現象 pp.1472-1485
Published Date 2018/10/25
DOI https://doi.org/10.11477/mf.1403201497
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 We compared the diagnostic abilities of white light imaging and NBI(narrow-band imaging)for the lateral margin of 60 early gastric cancers detected after Helicobacter pylori eradication. Regarding the lesions located in the gastric angle, body and fornix(43 cases), we investigated the mucosa surrounding the lesions by magnifying endoscopy and histology. The diagnostic accuracy of the lateral margin by white light imaging and NBI was 65% and 98.3%, respectively ; the latter was significantly higher than the former. In addition, magnifying endoscopy diagnosed the surrounding mucosa as atrophic area(21 cases, 48.8%), fundic glands area(3 cases, 7.0%), and intermediate zone(19 cases, 44.1%). Histologically, the surrounding mucosa of 31 cases(72.1%)was determined as the intermediate zone, which exhibited the fundic glands and pyloric metaplasia and/or intestinal metaplasia. Often, the intermediate zone appears with uneven coloration and surface structure, which tend to restrict the recognition of lesions by white light imaging. In contrast, NBI without magnification or with slight magnification can readily detect and delineate the lesions, highlighting the potential utility of NBI screening without magnification.

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