Early Gastric Cancer Diagnosed after Helicobacter pylori Eradication, Report of a Case Masashi Kawamura 1 , Shin Ichihara 2 , Hiroshi Naganuma 3 , Rie Shibuya 3 , Tatsuya Kikuchi 1 , Yoshitaka Sakai 1 , Futoshi Nagasaki 1 , Eiki Nomura 1 , Noriaki Suzuki 1 , Eri Saito 1 , Yutaka Konno 4 1Department of Gastroenterology, Sendai City Hospital, Sendai, Japan 2Department of Pathology, Sapporo-Kosei General Hospital, Sapporo, Japan 3Department of Pathology, Sendai City Hospital, Sendai, Japan 4Konno Internal Medicine Clinic, Sendai, Japan Keyword: 早期胃癌 , 胃型形質 , H. pylori除菌 , NBI , 拡大内視鏡 pp.820-825
Published Date 2016/5/25
DOI https://doi.org/10.11477/mf.1403200649
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 A female patient in her 70's who received Helicobacter pylori eradication therapy 13 years ago was referred to our hospital for further examination. Conventional endoscopic findings showed a discolored, slightly protruding lesion measuring approximately 3 mm that was located at the anterior wall of the middle gastric corpus. Magnifying endoscopy with narrow-band imaging showed minute granular structures with a demarcation line. An early stage gastric cancer was suspected because of the irregular microsurface and microvessel pattern. Histopathologic findings of the resected specimens by ESD treatment revealed a well-differentiated, MUC5AC-positive adenocarcinoma. Furthermore, normal fundic glands were seen beneath the carcinoma. The final pathological stage was pStage I[3×3 mm, tub1, pT1a, ly(−), v(−), HM0, VM0]. This case was diagnosed as minute early gastric cancer with foveolar epithelium differentiation, after eradication therapy.

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