Gastric Ulcer in Children Yoshiko Nakayama 1 1Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan Keyword: 小児 , 胃潰瘍 , H. pylori , AGML , 好酸球性胃腸炎 pp.907-912
Published Date 2017/6/25
DOI https://doi.org/10.11477/mf.1403201105
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 The rate of occurrence of peptic ulcer disease is low in childhood, with a predominance of duodenal ulcers over gastric ulcers(1.5〜10:1). Apart from the gastric ulcers caused by Helicobacter pylori, most gastric ulcers in children are secondary to and associated with underlying disorders such as infections ; hypersecretory state, as in Zollinger-Ellison syndrome ; eosinophilic gastroenteritis with allergy ; use of medications such as NSAIDs ; or extreme physiologic stress.

 Patients with AGML(acute gastric mucosal lesion)present with acute abdomen, frequent vomiting, and hematemesis. AGML appears in young children as an acute infection of H. pylori.

 The role of endoscopy in the diagnosis of gastric ulcer is crucial to visualize the gastric mucosal abnormalities, and more importantly, to obtain tissue biopsies for the diagnosis of etiology.

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