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要旨●胃癌の基本的な病理学的分類として,組織型分類,癌の間質量・浸潤増殖様式,脈管侵襲,生検組織診断分類(Group分類)について概略した.組織型分類は「胃癌取扱い規約」とWHO分類で類似しているが,前者は組織形態による分類であり,後者は組織形態と分化度を組み合わせた分類という違いがある.そのために低分化腺癌の取り扱いが異なっている.しかし,その違いもWHO分類のコンセプトが変わるにつれて少なくなってきている.また,組織型の診断が一致をみないことは昔から問題にされており,解決策として胃癌を2分類するLaurenや中村の分類が用いられている.目的に応じた組織型分類の使い分けが必要である.
For pathological classification of gastric cancer, I reviewed histological classification, cancer stromal volume, tumor infiltrative pattern into the surrounding tissues, lymphatic and venous invasion, and histological diagnosis of gastric biopsy(Group Classification). The histological classification of Japanese classification of gastric carcinoma is different from the WHO classification. The former is classified based on morphology, whereas the latter is classified based on morphology and differentiation of carcinoma. Therefore, the handling of poorly differentiated adenocarcinoma is different. However, because the WHO classification is revised, the difference has decreased. In the past, the histological type of gastric cancer were not in agreement among the pathologists. Thus, the Lauren classification or Nakamura classification are clinicopathologically used. It is necessary to properly use the histological classification depending on the purpose.
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