Stomach and Intestine(Tokyo) Volume 51, Issue 5 (May 2016)

Magnification Endoscopy for Early Neoplasms in the Barrett's Esophagus Kenichi Goda 1 , Akira Dobashi 1 , Yuko Hara 1 , Yamato Ban 1 , Nana Shimamoto 1 , Shunsuke Kamba 1 , Masakuni Kobayashi 1 , Masafumi Chiba 1 , Naoki Mori 1 , Kazuki Sumiyama 1 , Hisao Tajiri 1 , Takehiro Mitsuishi 2 , Shinichi Hirooka 2 , Masahiro Ikegami 2 1Department of Endoscopy, The Jikei University School of Medicine, Tokyo 2Department of Pathology, The Jikei University School of Medicine, Tokyo Keyword: Barrett食道 , Barrett食道癌 , 表在癌 , dysplasia , 内視鏡診断 , narrow band imaging pp.573-581
Published Date 2016/5/24
  • Abstract
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 BE(Barrett's esophagus)is a metaplastic condition that occurs as a result of gastroesophageal reflux disease. BE is also a precursor to esophageal adenocarcinoma, which, even though still rare in Japan, is one of the most rapidly increasing cancers in Western countries. However, over the past few decades the prevalence of gastroesophageal reflux diseases has significantly increased in Japan. This increase is likely to result in an incremental rise in BE and the associated inherent risk of adenocarcinoma.

 Because of the poor prognosis of late-stage adenocarcinoma in Barrett's esophagus, it is important to detect early neoplasias in BE patients. However, endoscopic identification of early neoplasms remains subjective and not sufficiently reliable, thus, making the targeted therapy extremely difficult.

 During the last decade, newly-developed imaging technologies combined with magnification endoscopy have enabled the identification of early neoplasias in BE patients. This article focuses on such advanced imaging technology, particularly, narrow band imaging, and provides an overview of the technologies, their practical applicability, current status, and future challenges.

Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.


51巻5号 (2016年5月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院