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Diagnosis and Treatment of Pseudomyxoma Peritonei Hideaki Yano 1 , Yoshimasa Gohda 1 , Ryuichiro Suda 1 , Toru Igari 2 1Department of Surgery, Division of Colorectal Surgery, National Center for Global Health and Medicine, Tokyo 2Clinical Laboratory and Pathology, National Center for Global Health and Medicine, Tokyo Keyword: 腹膜偽粘液腫 , 虫垂粘液癌 , 腹膜切除 , 完全減量切除 , 腹腔内温熱化学療法 pp.520-526
Published Date 2014/4/25
DOI https://doi.org/10.11477/mf.1403114123
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 Pseudomyxoma peritonei is a rare clinical entity characterized by mucinous ascites that most commonly originates from a low-grade mucinous adenocarcinoma of the appendix. It is progressive and can be fatal if untreated ; however, bloodborne or nodal metastasis is uncommon. The behavior of mucinous tumors suggests that they are, at best, a borderline malignancy with a spectrum of pathology ranging from indolent to aggressive mucinous adenocarcinoma. Because tumors limited to the appendiceal wall can be cured by complete excision, it generally considered appropriate to classify them as adenomas and early removal should be recommended. Tumors with extra-appendiceal neoplastic epithelium are classified as mucinous adenocarcinomas and subcategorized as low- or high-grade. Complete cytoreduction combined with hyperthermic intraperitoneal chemotherapy is now considered the standard of care, despite its associated morbidity.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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