Primary Diffuse Infiltrating Type Colorectal Cancer, Report of a Case Nobuyoshi Takizawa 1,2 , Hiroshi Matsuzaka 1,2 , Koujirou Niho 1,2 , Kyoko Fukawa 1,2 , Kazumasa Muta 1,2 , Takafumi Yamada 1,2 , Tomohito Chaen 1,2 , Norimoto Nakamura 1,2 , Yoshiharu Chijiiwa 2 , Shinji Kouno 3 , Makoto Takahashi 4 , Ayako Goto 4 , Kazuhiko Nakamura 5 , Ryouichi Takayanagi 5 , Minako Hirahashi 5 , Yoshinao Oda 1 1Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Department of Internal Medicine, Gastroenterology, Harasanshin Hospital, Fukuoka, Japan 3Department of Pathology, Harasanshin Hospital, Fukuoka, Japan 4Department of Internal Medicine, Fukuoka City Hospital, Fukuoka, Japan 5Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Keyword: びまん浸潤型大腸癌 , 癌性リンパ管症 , linitis plastica , 若年者大腸癌 , 4型大腸癌 pp.1059-1066
Published Date 2013/6/25
DOI https://doi.org/10.11477/mf.1403113865
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 A 33-year old woman visited the clinic because of lower abdominal pain. Colonoscopy revealed stricture of the sigmoid colon with an open ulcer. Although, we couldn't detect definite findings of malignancy in this lesion, we found reddish mucosa at the edge of the ulcer. And then we noticed other factors, such as cobblestone-like appearance and tapering stricture, which indicated diffuse infiltrating-type colorectal cancer. The biopsy specimens showed poorly differentiated adenocarcinoma. The resected specimen revealed moderately to poorly differentiated adenocarcinoma with transmural invasion, accompanied by marked desmoplastic reaction and prominent lymphatic permeation widely spread into the colonic wall.

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