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炎症性腸疾患(IBD)の腸管外合併症を明らかにすることを目的としてアンケート調査を施行した.アンケートは九州全域の33施設から回答が得られ,母数はCrohn病(CD)2,227例,潰瘍性大腸炎(UC)3,499例であった.腸管外合併症の有病率はCDで43.9%,UCで28.9%であり,UCに比較してCDが多かった.臓器系統別の腸管外合併症有病率はCD,UCとも肝・胆道系,皮膚・粘膜系,筋骨格系が多く,その内訳ではCDは口腔内アフタ(6.2%),関節炎・関節症(5.5%),膵炎・高アミラーゼ血症(5.4%),胆石症(4.6%)が多く,結節性紅斑(1.5%),尿路結石(1.7%)が続いた.UCでは関節炎・関節症(4.9%),膵炎・高アミラーゼ血症(2.9%)が多く,口腔内アフタ(1.9%),胆石症(1.3%),尿路結石(0.9%)が続いた.なお,CD,UCとも精神・神経障害が約3%に認められた.
The incidence of extra-intestinal complications was analized in 2,227 patients with CD(Crohn's disease), in 3,499 patients with UC(ulcerative colitis). The overall incidence of extraintestinal complications was 43.9% in CD and 28.9% in UC. In CD, aphthous stomatitis(6.2%), arthritis(5.5%), hyperamylasemia or pancreatitis(5.4%), gallstone(4.6%), erythema nodosum(1.5%)and urinary stone(0.9%)occurred frequently. In UC, frequent accompanying complications were arthritis(4.9%), hyperamylasemia or pancreatitis(2.9%), aphthous stomatitis(1.9%)gallstone(1.3%)and urinary stone(1.7%). The physician should keep in mind the complications likely to accompany inflammatory bowel disease.
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