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Primary Malignant Melanoma of the Esophagus, Report of Two Cases Seiyo Ikeda 1,2 , Kunio Takagi 1,2 , Iwao Kinoshita 1,2 , Kenji Kumakura 3 , Takeshi Kasuga 4 1Dept. of Surgery, Cancer Institute Hospital pp.1175-1182
Published Date 1971/8/25
DOI https://doi.org/10.11477/mf.1403111629
  • Abstract
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 Primary malignant melanoma of the esophagus is an extremely rare disease, and not more than 40 cases have been reported so far in the literatures of the world, including Japan.

 In this paper, two experienced cases of primary malignant melanoma of the esophagus are presented.

 The first case is a fifty-year-old male patient with chief complaint of swallowing difficulty. X-ray exmination showed an oval-shaped polypoid defect in the upper one third of the thoracal esophagus, and the diagnosis of malignant melanoma was made by esophagofiberscopic biopsy. On Aug. 9th 1968, subtotal esophagectomy was performed. In the resected specimen, there was seen a pedunculated mass, black in color, and measuring 4×2×1.5 cm. No lymph node metastasis was identified. The postoperative course was uneventful, and the patient has been well two years after operation.

 The second case was a sixty-two-year-old male patient with the chief complaint also of swallowing difficulty. X-ray showed an egg-sized defect in the lower one third of the thoracal esophagus which was suggestive of sarcoma. On Oct. 4th 1967, esophagocardiectomy was performed. The tumor was localized, dark-brown in color, and measured 6×5×4 cm. One lymph node metastasis was identified. Three months after operation, recurrent (left axillary lymph) node metastasis was confirmed, and the patient died one year and two months later due to cachexia.

 Histologically alveolar construction showing nevoid and/or epithelioid pattern was observed, and socalled junctional change was seen in the adjacent squamous epithelium.


Copyright © 1971, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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