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A CASE OF MÉNÉTRIER'S DISEASE Terutoshi Murata 1 1Dept. of Internal Med., School of Medicine, Tohoku Univ. pp.1133-1137
Published Date 1969/9/25
DOI https://doi.org/10.11477/mf.1403111041
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 A case of Ménétrier's disease was recently encountered in a 38-year-old man. Toward the end of March 1966, he had caught cold followed a few days later by nausea and epigastralgia. On April 23 edema was noticed on his face and in the left lower extremity. On May 2 he had a bout of tetanic attack. Edema was observed in his right lower extremity as well.

 At the time of admission, the liver, of normal soft consistency, was palpated about the breadth of a finger below the costal margin. No anemia was noticed. Of serum electrolytes, K was 2.90 mEq/l, and total serum protein was as low as 4.0 g/dl. Intragastric secretion rate during seven hours after Ⅰ31 PVP 58μc had been intravenously injected was 1.1 per cent. The Gordon's test was 8.3 per cent. X-ray examination revealed giant rugae mainly in the greater curvature side of the corpus ven triculi. On Aug. 1, subtotal gastrectomy (two-thirds) was performed followed by Billroth Ⅱ anastomosis.

 Postoperative serum protein levels rose up to 6.9 g/dl on Sept. 12. The Gordon's test on Nov. 21 was 0.74 per cent, a normal figure. Edema in the left lower extermity was still noticiable, suggesting of lymphedema.

 In the resected stomach was noticed mucosal hypertrophy and enlargement of lymph vessels in the lamina propria. Biopsy of the liver demonstrated a number of microabscess around central veins and granulocytic infiltration near Glisson's capsules. Sample excision of V. saphena magna showed no abnormality.

 As of Feb. 1968 the patient is having favorable progress toward recovery.


Copyright © 1969, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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