Amebic Colitis Diagnosed by Biopsy after Four Years of Treatment as Ulcerative Colitis, Report of a Case Yoshiro Kubota 1 , Fumio Konishi 1 , Tetsuichiro Muto 1 1The First Department of Surgery, Facully of Medicine, University of Tokyo pp.653-656
Published Date 1986/6/25
DOI https://doi.org/10.11477/mf.1403110356
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 A 34 year-old man vislted our hospltal, complamlng of bloody dlarrhea. He had no history of being abroad.Proctoscoplcal study revealed edematous and reddish mucosa with muliple eroions in the rectum in May 1980. These findings were most suggesive of ulceraive colitis and consequently predonlsolone suppository and salazosulfapyridine were started,With these medications symptoms were relieved temporarily only to enter into the period of frequently alter-nating relapses and remissions of bloody diarrhea. Endoscopical examination performed in February 1981revealed edematous and reddish mucosa with multiple erosions through the entire colon.

 Histological findings of biopsy specimen showed diffuse inflammatory cell infiltration in colonic epithelium without goblet cell depletion and crypt abscess. Based on these findings, in the next four years he was again given the treatment directed to chronic ulcerative colitis. However, biopsy specimen taken in May 1984 demonstrated Entamoeba histolytica at last. Immediately metronidazole was administered for one week resulting in the disappearance of the lesions.  It seems most important to take amebic colitis into consideration in the differential diagnosis of inflammatory bowel disease.

Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.


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