Japanese

Ulcerative Colitis Complicated with Multiple Colorectal Cancers Developing over a Short Term, Report of a Case and Review of the Literature Yayuki Hioki 1 1Department of Gastroenterology, Seirei Mikatahara General Hospital Keyword: 潰瘍性大腸炎 , 大腸癌 pp.1155-1164
Published Date 1996/8/25
DOI https://doi.org/10.11477/mf.1403104285
  • Abstract
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 A 43-year-old man with ulcerative colitis had been followed up, since 1981, for 13 years. Colonoscopy disclosed two lesions on the rectum (Ra) and the rectosigmoid colon (Rs) in 1993, only one year and four months after the previous examination. Barium enema (Fig. 1) and colonoscopy (Fig. 2) showed a slightly irregular elevated lesion on the Ra and a nodular protruded lesion on the Rs. Biopsy specimen revealed both lesions were cancers, so proctocolectomy was performed. Pathological examination of the resected specimens (Fig. 4) showed that the slightly elevated lesion on the Ra consisted of a well differentiated adenocarcinoma invading the submucosa and a mucinous carcinoma invading the serosa. It also showed that the nodular protruded lesion on the Rs consisted of well differentiated adenocarcinoma invading the mucosa. Surrounding these cancers was low or high grade dysplasia. Our case was the 42nd case of ulcerative colitis complicated with multiple colorectal cancers in Japan. Cancers developing from ulcerative colitis are suspected to grow rapidly compared with the growth rate of ordinary colon cancers.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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