Diffuse Gastritis Complicating Ulcerative Colitis, Report of a Case Tatsuya Mikami 1 , Shinsaku Fukuda 2 , Yoshiharu Uno 1 , Masanori Tanaka 3 , Yoshihiro Sasaki 1 1The First Department of Internal Medicine, Hirosaki University School of Medicine 2Department of Endoscopy, Hirosaki University School of Medicine 3The Second Department of Pathology, Hirosaki University School of Medicine Keyword: 潰瘍性大腸炎 , 胃炎 pp.575-579
Published Date 2001/3/25
DOI https://doi.org/10.11477/mf.1403103195
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 A 27-year-old woman with nausea, vomiting, epigastralgia, and hematochezia was admitted to our hospital. The barium enema study showed lead-pipe like appearance and the total colonoscopy revealed diffuse erosions and redness continuously from the rectum to cecum. Biopsy specimens showed the diffuse severe mucin depletion, crypt atrophy, crypt distortion, and crypt abscesses, which were consistent with the ulcerative colitis. On the other hand, upper gastrointestinal endoscopy showed diffuse erosions and redness in the gastric mucosa. Endoscopic mucosal resection was undergone and the specimens revealed the diffuse moderate chronic active gastritis including the abscess in the gastric pit. Helicobacter pylori (H.pylori) was considered to be negative because 13C-urea breath test, anti-H.pylori immunoglobulin G antibody, and culture were all negative.

 After taking mesalazine and prednisolone, she underwent colonoscopy. Endoscopic findings showed active inflammation yet, then betamethasone was added topically. Though she never took proton pump inhibitor or histamine receptor antagonist, upper gastrointestinal endoscopy showed almost normal gastric mucosa after the remission of ulcerative colitis.

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