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The Clinical Course of Gastroduodenitis Associated with Ulcerative Colitis Kazutoshi Hori 1,2 , Hiroki Ikeuchi 3 , Motoi Uchino 3 , Nobuyuki Hida 1,4 , Takeshi Kusaka 4 , Yoshio Ohda 4 , Shiro Nakamura 4 , Takayuki Matsumoto 4 , Fumihiko Toyoshima 2 , Toshihiko Tomita 2 , Yongmin Kim 2 , Hiroto Miwa 2 1Department of Endoscopic Center, Hyogo College of Medicine, Nishinomiya, Japan 2Division of Upper Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan 3Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan 4Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan Keyword: 潰瘍性大腸炎 , 上部消化管病変 , 胃炎 , 十二指腸炎 , 治療 pp.1549-1559
Published Date 2009/9/25
DOI https://doi.org/10.11477/mf.1403101756
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 Friable and granular mucosa, and multiple aphthae were identified as characteristic findings of gastroduodenitis associated with ulcerative colitis(GDUC)in our previous study. These endoscopic findings were observed in 24(8.6%)of 280 patients with ulcerative colitis(180 with pancolitis, 175 with colectomy). Seven GDUC patients were treated with powdered mesalazine(crushed tablets), and the remission of GDUC was achieved in 5 of the 7 patients. Repeat upper endoscopy was performed for 43 GDUC-negative patients. The development of GDUC was observed in 2(4.7%)patients 22 months on average after initial endoscopy. In a total of 26 GDUC patients, 2 patients had anemia due to duodenal bleeding on friable mucosa, and 2 had duodenal stenosis as a result of chronic inflammation on friable mucosa. These results suggest that GDUC is not a rare complication and is a condition that requires therapy.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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