Crohn's Disease Unsuccessfully Treated with Long-term Home Enteral Nutrition, Report of Two Cases Takanori Fujiki 1 , Toshifumi Ashida 1 , Kaori Fujiya 1 , Atsuo Maemoto 1 , Arimi Sasaki 1 1The Third Department of Internal Medicine, Asahikawa Medical College Keyword: Crohn病 , 経腸栄養療法 , 在宅経腸栄養療法 , 成分栄養療法 pp.1301-1306
Published Date 1999/9/25
DOI https://doi.org/10.11477/mf.1403102827
  • Abstract
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 Nutritional therapy with elemental diet formula (ED) is now widely accepted by Japanese physicians and patients as a potent remission-inducing therapy for active Crohn's disease. However, the effectiveness of this ED therapy for remission-maintenance in these patients is still controversial. We report two cases of Crohn's disease, who have undergone the home ED therapy for the last 10 years. In both cases, typical strictures in the small intestine due to cobblestone lesions of Crohn's disease were present. These lesions did not improve during the first several years, and they required surgery. After one or two years after the surgical resections of the small intestine, recurrent lesions at the site of the intestinal anastomosis were noted by radiological examination, but the patients continued the home ED. Through the experience of these cases, we think that the indication and/or cost-benefit of home ED therapy should be re-evaluated by a large-scale randomized controlled trial.

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