Clinical Features and Proximal Extensionof Ulcerative Proctitis Takahiro Ito 1 , Kotaro Okamoto 1 , Mikihiro Fujiya 1 , Ryuji Sugiyama 1 , Toshie Nata 1 , Yoshiki Nomura 1 , Nobuhiro Ueno 1 , Kentaro Itabashi 1 , Shin Kashima 1 , Chisato Ishikawa 1 , Yuhei Inaba 1 , Kentaro Moriichi 1 , Hiroki Tanabe 1 , Yutaka Kohgo 1 , Atsuo Maemoto 2 , Toshifumi Ashida 2 , Jiro Watari 3 , Yusuke Saitoh 4 1Department of Medicine, Division of Gastroenterology and Hepatology/Oncology, Asahikawa Medical College, Asahikawa, Japan 2IBD Center, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan 3Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan 4Digestive Disease Center, Asahikawa City Hospital, Asahikawa, Japan Keyword: 潰瘍性大腸炎 , 直腸炎型 , 口側進展 , skip病変 , 予後 pp.1541-1548
Published Date 2009/9/25
DOI https://doi.org/10.11477/mf.1403101755
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 To elucidate the incidence and risk factors for proximal extension of ulcerative colitis (UC) in the Japanese population, we investigated the backgrounds and clinical courses of UC patients according to our clinical records. 23% of the UC patients had been initially diagnosed as having proctitis type, while 41.9% of them exhibited proximal extension. The gender, age or severity at the time of initial diagnosis and the presence of skip lesions were not found to be associated with the incidence of the proximal extension in UC. Whereas the cumulative rate of surgery was 12.2% at 5 years and 23.3% at 10 years, no surgery was required for the patients without proximal extension. 80% of the patients who exhibited proximal extension needed an operation within 2 years. No colitic cancer was detected in the patients with proctitis. Proximal extensions were thus regarded as being important risk factors leading to surgical operations in patients with ulcerative proctitis. Further analysis is therefore needed to identify the risk factors for the proximal extension of certain types of proctitis.

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