Schwannoma of the Sigmoid Colon, Report of a Case Tomonori Ishioka 1 , Mamoru Nishizawa 1 , Yasuo Ookura 2 1Tokyo Metropolitan Cancer Detection Center 2Department of Pathology, School of Medicine, University of Tsukuba Keyword: S状結腸 , 粘膜下腫瘍 , 神経鞘腫 pp.539-544
Published Date 1991/5/25
DOI https://doi.org/10.11477/mf.1403102537
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 A 63-year-old female underwent barium enema and colonofiberscopy because of positive fecal occult blood.An apparently elevated lesion with a central depression was visualized in the sigmoid colon by barium enema(Figs.1 and 2).Profile appearance showed a gently rising elevation indicative of submucosal tumor.The margin was rigid at the bottom of the lesion, suggesting that epithelial lesion could not be entirely ruled out.The lesion was diagnosed as submucosal tumor by endoscopy based on a variety of its characteristics(Fig.3).Sigmoid colectomy was performed.In the resected specimen was a submucosal tumor with a central depressions, measuring 1.6×1.4×1.4 cm in size(Fig.4).The cut surface of the tumor had yellowish hue, which was considered to be one of the most crucial characteristics of schwannoma.Histological examination showed interlacing fascicular pattern(Fig.5 a)and palisading of nuclei(Fig.5 b).Loose, reticular and poor cellular patterns corresponded to Antoni type B(Fig.5 c).In addition, the tumor was positive for S-100 protein staining(Fig. 6).Based on these findings the lesion was diagnosed as schwannoma.

 Only 21 cases of schwannoma of the colo-rectum have been reported to date in Japan,14 of which arising from the rectum(Table 1).Schwannoma of the colon as we reported here is thus rare.

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