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Collision Carcinoma at the Cardia Diagnosed by Endoscopy, Report of a Case Takafumi Andoh 1 , Yuji Oka 1 , Susumu Kurokawa 1 , Kimitomo Morise 4 , Kazuo Kusugami 4 1Department of Internal Medicine Nagoya Firsu Hospital 2The Firasu Department of Internal Medicine, Nagoya University School of Medicine Keyword: 衝突癌 , 噴門部癌 pp.313-319
Published Date 1991/3/25
DOI https://doi.org/10.11477/mf.1403102489
  • Abstract
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 A 52-year-old man was admitted to our hospital complaining of epigastric pain. Upper gastrointestinal series and endoscopic examination showed a Ⅱc + Ⅱa lesion bordering on a small Ⅱc lesion at the cardia of the stomach with sliding hernia (Fig. 1 and 3). Biopsy specimens obtained from the Ⅱc + Ⅱa and small Ⅱc lesions demonstrated squamous cell carcinoma and adenocarcinoma respectively (Fig. 4).

 Proximal gastrectomy with partial esophagectomy was performed and examination of the resected specimen showed a Ⅱc + Ⅱa lesion measuring 19×15 mm and a Ⅱc lesion measuring 9×6 mm located close to each other (Fig. 6). Histologically, the Ⅱc + Ⅱa lesion consisted of squamous cell carcinoma infiltrating into the submucosa, whereas the small Ⅱc lesion was composed of adenocarcinoma localized in the mucosa. The serial sections revealed the area where these two carcinomas collide with each other, and there was no histological transition between them (Fig. 7).

 Thus, these histological findings of the two cancerous lesions fit well with the concept of collision carcinoma.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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