Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
- サイト内被引用 Cited by
要旨 通常内視鏡画像と水中NBI拡大内視鏡観察にて約3mm大の関心領域を設定し,同部の組織型診断を行った.さらに3%酢酸撒布を行い表面構造から組織型を診断した.関心領域の組織型は高分化型39例,中分化型12例,低分化型2例であった.拡大内視鏡所見は表面構造と血管構造に分け,表面構造が不明瞭な場合は血管構造に基づいて診断した.この結果,NBI拡大観察では62%(33例)で表面構造が不明瞭であったが,酢酸を撒布することで,33例中31例(94%)で表面構造が確認された.結果:NBI拡大内視鏡による組織型正診率は高分化型で69%(27/39),中分化型で58%(7/12),低分化型で50%(1/2),合計66%(35/53)であったが,酢酸NBI拡大内視鏡による組織型診断正診率は高分化型90%(35/39),中分化型92%(11/12),低分化型100%(2/2),合計91%(48/53)であり,McNemar検定でp=0.013と有意差を認めた.酢酸撒布NBI拡大内視鏡は胃癌組織型診断に有用である.
Endoscopic diagnosis of histology for the early gastric cancer is very important, because the risk of lymph node metastasis has a deep relationship to histology. A 3mm area was decided by white light and NBI magnified endoscopy to clarify the relationship between the endoscopic and histological findings. The histology of the target area ; Well, moderate and poorly differentiated adenocarcinoma was 39,12 and 2, respectively.
Result : the accuracy of NBI magnified endoscopy for well, moderate and poorly differentiated adenocarcinoma was 69%(27/39),58%(7/12)and 50%(1/2), respectively. And the total accuracy of NBI magnified endoscopy was 66%(35/53). The accuracy of acetic acid NBI magnified endoscopy of well, moderate, poorly differentiated adenocarcinoma was 90%(35/39),92%(11/12)and 100%(2/2). And, the total accuracy was 91%(48/53). There was a significant difference between NBI magnified and acetic acid NBI magnified endoscopy(p=0.013). Therefore,NBI magnified endoscopy with acetic acid is a useful method for the histological diagnosis of early gastric cancer.
Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.