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Epidemiology and Etiology of Collagenous Colitis Kinichi Hotta 1 , Tsuneo Oyama 1 , Yoshinori Miyata 1 , Akihisa Tomori 1 , Akiko Takahashi 1 , Yoko Kitamura 1 , Tomoaki Shinohara 1 1Department of Gastroenterology, Saku Central Hospital, Saku, Japan Keyword: collagenous colitis , microscopic colitis , 疫学 , 病因 , 薬剤起因性 pp.1966-1972
Published Date 2009/12/25
DOI https://doi.org/10.11477/mf.1403101814
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 In western countries, the diagnosis of collagenous colitis and lymphocytic colitis are made in 10-20% of cases investigated for watery diarrhea. Based on some epidemiologic studies, annual incidence of collagenous colitis was 2.3~7.1/100,000 inhabitants. Some investigators reports rising incidence of collagenous colitis. The median age at diagnosis of collagenous colitis was 58~70 years old and female ratio was 83~89%. Several theories on the etiology of collagenous colitis, such as drugs, genetics, bile acid malabsorption, infections, nitric oxide and abnormal collagen metabolism, have been investigated. Nevertheless, the cause of collagenous colitis has not been sufficiently clarified.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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