Evaluation of the Response to Chemotherapy in Advanced Gastric Cancer by Contrast-enhanced Harmonic EUS Using Sonazoid® Mumon Okada 1 , Masaki Takayama 1 , Yoshiaki Nagata 1 , Masanori Kawasaki 1 , Yutaka Asakuma 1 , Yasushi Umehara 1 , Sigenaga Matsui 1 , Masayuki Kitano 1 , Masatosi Kudo 1 1Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka-Sayama, Japan Keyword: 進行胃癌 , 化学療法 , Sonazoid® , 造影EUS検査 , vascularity pp.1871-1877
Published Date 2009/11/25
DOI https://doi.org/10.11477/mf.1403101801
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 The importance of evaluation of the response to chemotherapy in primary gastric tumor is accepted widely in Japan. In this study, we evaluated the response to chemotherapy in primary gastric tumor by contrast-enhanced harmonic EUS(CEH-EUS)using Sonazoid® and examined the utility of CEH-EUS using Sonazoid®. CEH-EUS using Sonazoid® is a new method of evaluating primary gastric tumor by not only a change of its form but also its vascularity and we are able to evaluate the response to chemotherapy by CEH-EUS using Sonazoid® in primary gastric tumor, which is difficult to evaluate by conventional endoscope and barium roentgenograms. Also, there is a significant association between tumor angiogenesis and prognosis of patients and metastasis by various solid tumors including gastric cancer and we think that correct evolution of tumor vascularity helps in the prognosis of patients and metastasis.

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