Endoscopic Evaluation of Primary Tumor in Metastatic Colorectal Cancer Patients who Received Chemotherapy Madoka Takao 1 , Kentaro Yamazaki 2 , Narikazu Boku 2 , Masaki Tanaka 2 , Naomi Kakushima 2 , Kohei Takizawa 2 , Hisatomo Ikehara 1 , Hiroyuki Matsubayashi 1 , Yuichiro Yamaguchi 1 , Hiroyuki Ono 1 1Division of Digestive Endoscopy, Shizuoka Cancer Center Hospital, Shizuoka, Japan 2Division of Gastrointestinal Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan Keyword: 大腸癌 , 化学療法 , RECIST , 内視鏡 , 治療効果判定 pp.1879-1886
Published Date 2009/11/25
DOI https://doi.org/10.11477/mf.1403101802
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 To assess the response to chemotherapy of metastatic colorectal cancer, the usefulness of endoscopy is uncertain and RECIST is generally used. Endoscopic evaluation was carried out in patients who received chemotherapy without prophylactic surgery for primary tumor. For most patients with PR or SD in RECIST, the primary tumor was not progressive. Therefore, periodic endoscopic examination may not be necessary when the disease is stable according to RECIST. However, for patients with PD in RECIST, or when intestinal stenosis has been pointed out by CT, the incidence of intestinal stenosis is rather high. Therefore endoscopic examination may be necessary to evaluate the extent of stenosis in such situations. Further investigation is needed to show how endoscopic evaluation can compensate for the weak points of CT.

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