Evaluation Criteria Concerning the Efficacy of Chemotherapy for Advanced Gastric Cancer Wasaburo Koizumi 1 1Department of Internal Medicine, Kitasato University School of Medicine Keyword: 胃癌 , 化学療法 , 効果判定 , RECIST , 胃癌取扱い規約 pp.987-998
Published Date 2005/6/25
DOI https://doi.org/10.11477/mf.1403100216
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The efficacy of chemotherapy for gastric cancer has been evaluated by Japanese criteria for a long time in Japan. In 1999 RECIST criteria was reported by NCI, EORTC, and NCI Canada as a new version of WHO criteria. The author reported the differences between RECIST and Japanese criteria. Some problems were pointed out. The biggest problem was that primary gastric lesion was not evaluated as a target lesion in RECIST criteria. Primary gastric lesion should be evaluated by Japanese criteria because of the strong relation it has to survival and the increased patient enrolements even though they only have a primary lesion. RECIST will be the absolute criteria for evaluating the response of all solid tumors but the concomitant response evaluation of primary gastric lesions should be surrogate criteria in gastric cancer treatment.

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