Inflammatory Esophagogastric Polyp with Stromal Atypia, Report of a Case Yasuhiro Takaki 1 , Yuji Murakami 1 , Takahiro Beppu 1 , Akiko Kubota 1 , Toshiyuki Matsui 1 , Nobuaki Nishimata 2 , Keisuke Ikeda 2 , Akinori Iwashita 2 1Department of Gastroenterology, Fukuoka University, Chikushi Hospital, Chikushino, Japan 2Department of Pathology, Fukuoka University, Chikushi Hospital, Chikushino, Japan Keyword: 食道胃接合部 , 炎症性ポリープ , stromal atypia , pseudomalignant erosion pp.321-325
Published Date 2008/3/25
DOI https://doi.org/10.11477/mf.1403101296
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 A 54-year-old patient underwent an endoscopic examination for heartburn of 10-years standing and vomiting. At 12 o'clock at the squamocolumnar junction(SCJ), an evident, raised polyp measuring about 8 mm was recognized. This lesion was covered with whitish mucosa partly tinged with redness and had a lustrous surface. Its oral side was marked by the presence of reflux esophagitis. An X-ray examination showed a slightly elevated lesion(measuring 10×10 mm)with a relatively smooth, granular surface at the esophagogastric junction that was characterized by an esophageal hiatal hernia. And the lesion was also accompanied by a swollen gastric fold. Histopathological examination of the biopsy specimen showed a chronically mildly inflamed esophageal mucosa with hyperplastic squamous epithelium and a proliferation of small vessels at the stroma of the lamina propria. Atypical cells-short spindle cells and ovoid cells-were also noted in parts. However no pathological malignancy was detected. A diagnosis of a polyp of the esophagogastric junction(EGJ)with reactive atypia of the stroma was made. The patient was treated with an oral proton pump inhibitor(PPI). An endoscopic examination conducted about a month later indicated that the polyp appeared to have been reduced in size. The patient is currently under observation.

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