Segmental Hypoganglionosis of the Colon in an Adult, Report of a Case Yuji Murakami 1 , Nobuaki Nishimata 2 , Yasuhiro Takaki 1 , Takahiro Beppu 1 , Takashi Nagahama 1 , Toshiyuki Matsui 1 , Hiroshi Tanabe 2 , Akinori Iwashita 2 , Masayuki Hotokezaka 3 1Department of Gastroenterology, Fukuoka University, Chikushi Hospital, Chikushino, Japan 2Department of Pathology, Fukuoka University, Chikushi Hospital, Chikushino, Japan 3Department of Surgery 1, University of Miyazaki Hospital, Miyazaki, Japan Keyword: 大腸 , hypoganglionosis , 慢性偽性腸閉塞症 , 攣縮 pp.887-894
Published Date 2013/5/25
DOI https://doi.org/10.11477/mf.1403113840
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 A patient in his 30's was admitted to our hospital because of stomachache after a few days of constipation in January, 2007. He had been diagnosed as ileus by abdominal X-ray examination and hospitalized urgently. Endoscopy revealed an ulcerous lesion in the descending colon. Barium enema radiography demonstrated a thumb-printing lesion and a spastic lesion at the junction from the descending colon to the sigmoid colon, seeming by to the permanent narrow segment. Subtotal colectomy of about 20cm was performed on the narrow segment and the histologic examination of the resected specimen showed the atrophic change of the intraluminal nerve plexuses generally and remarkable reduction in the number of ganglion cells in the narrow segment. He was diagnosed as having segmental hypoganglionosis of the colon.

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