Diagnosis of the Grade of Submucosal Invasion of Endoscopically Resected Colorectal Submucosal Carcinoma―Practice and Problems Yoichi Ajioka 1 , Shinji Tanaka 2 1Department of Pathology, Graduate School of Medicine, Medical and Dental Sciences, Niigata University, Niigata, Japan 2Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan Keyword: 大腸SM癌 , 内視鏡的切除 , SM浸潤距離 , SM浸潤度 , 病理学的根治度判定 pp.1501-1510
Published Date 2007/9/25
DOI https://doi.org/10.11477/mf.1403101198
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 As a part of a research project by the Japanese Soceity for Cancer of the Colon and Rectum, an investigation was made to elucidate the variation in diagnosis of submucosal invasion distance and its grading (less than 1,000μm or more) by pathologists. In regard to non-pedunculated lesions, the interobserver variation of the diagnosis of invasion distance was around 400μm, and the concordance was low muscularis mucosae in cases of "submucosal carcinoma with deformed musculsaris mucosae" and "submucosal carcinoma with disappearance of muscularis mucosae" (77.8%and 85.4%, respectively). In regard to pedunculated lesions, differentiation of ones with and without complex muscularis mucosae was not consistent among the pathologists. It is thought that variation in the interpretation of the guideline and the standardization of the diagnosis of submucosal invasion distance and its grading is required.

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