Differential Diagnosis of Non-neoplastic and Neoplastic Lesions Using Magnifying Chromoendoscopy Takahisa Matsuda 1 , Yutaka Saito 1 , Tsuyoshi Kikuchi 1 , Chizu Yokoi 1 , Shinsuke Kiriyama 1 , Haruhisa Suzuki 1 , Chika Kusano 1 , Masakatsu Fukuzawa 1 , Hajime Takisawa 1 , Daizo Saito 1 , Kuang-I Fu 2,3 , Yasushi Sano 2,4 , Takahiro Fujii 5 1Division of Endoscopy, National Cancer Center Hospital, Tokyo 2Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan 3Department of Radiology, Dokkyo University School of Medicine, Tochigi, Japan 4Gastrointestinal Center, Sano Hospital, Kobe, Japan 5TF Clinic, Tokyo Keyword: 大腸腫瘍 , 拡大内視鏡 , pit pattern診断 pp.781-785
Published Date 2007/4/26
DOI https://doi.org/10.11477/mf.1403101082
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 Differential diagnosis of malignant and benign colorectal lesions, using colonoscopy is of cardinal importance. Magnifying colonoscopy permits observation of the fine pit pattern, which may result in more accurate diagnosis regarding colorectal lesions at an earlier stage. We have conducted a prospective study to examine whether magnification and/or indigo carmine dye spraying is more reliable than the conventional view for such differential diagnosis. The overall diagnostic accuracy of magnification in addition to chromoendoscopy using indigo carmine was 95.6%, which is 10% and 5% more reliable than conventional endoscopy and chromoendoscopy, respectively. Additionally, that method was significantly superior to conventional endoscopy and chromoendoscopy (p<0.0001 and p=0.0152). Therefore, based on the results, we are able to conclude that the combination of magnifying colonoscopy and chromoendoscopy is the most reliable method for separating non-neoplastic at the present time from neoplastic lesions of the colon and rectum.

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