Immunodeficiency (including agammaglobu-linemia) ; a Case of Common Variable Immunodeficiency (CVID) with Multiple Colonic Ulcers Itaru Sasaki 1,2 1Department of Medicine and Bioregulatory Science Faculty of Medicine, Kyushu University Keyword: 免疫不全 , 分類不能型免疫不全症 , アポトーシス小体 pp.573-577
Published Date 2003/4/24
DOI https://doi.org/10.11477/mf.1403100917
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 The pathogenesis of gastrointestinal tract lesions in patients with primary immunodeficiency remains unknown. We present a case of CVID, a 23-year-old woman, suffering from multiple colonic ulcers, which were small and well-demarcated. Colonic biopsy specimens showed many apoptotic bodies, although she had no evidence of graft-versus-host disease or any other cause of apoptotic body increase. Therefore, these findings were thought to be a specific phenomenon at such a case as hers. It may be that immunodeficiency is associated with its own patterns of gastrointestinal inflammation that do not readily fit into established diagnostic categories.

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