Differential Diagnosis of Neoplastic/Non-neoplastic Colorectal Tumors by Using Magnifying Endoscopy Hiro-o Yamano 1 , Kouhei Kuroda 1 , Kenjiro Yoshikawa 1 , Kentarou Sato 1 , Masahito Nomoto 1 , Kenta Kodama 1 , Minoru Fujita 1 1Department of Gastroenterology Akita Red Cross Hospital, Akita, Japan Keyword: 内視鏡診断 , 拡大内視鏡 , pit pattern , 大腸腫瘍性病変 pp.1763-1771
Published Date 2006/12/25
DOI https://doi.org/10.11477/mf.1403100816
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 Recently, we can use magnifying endoscopy for endoscopic diagnosis of colorectal tumors. It is called “pit pattern diagnosis” when we diagnose pathological features from the magnified surface structure of colorectal tumors. In this article, in retrospective study, we investigatable ability of pit pattern diagnosis for differential diagnosis of neoplastic/non-neoplastic colorectal tumors. The subjects were 1,328 cases in which we could observe surface structure by using magnifying endoscopy, and which were taken from specimens after endoscopic or surgical resection in our hospital. We defined type I and II pit pattern as non-neoplastic, type III, IV and V pit pattern as neoplastic surface structure, and we calculated our accuracy through comparison with pathological diagnoses. The results showed a high rate of accuracy, with sensitivity ; 89.3 %, and specificity ; 96.2 %(p<0.01). On the other hand we made a wrong diagnosis in a few cases, for example ; we diagnosed low grade adenomas and lesions under 5 mm in size as non-neoplastic pit pattern, and inflammatory polyps and hyperplastic polyps as neoplastic ones. In conclusion, we proved that it is possible to make differential diagnosis of neoplastic/non-neoplastic colorectal tumors by using magnifying endoscopy. If we can carry out a prospective study about this same theme, that we will be able to achieve an even higher accuracy rate.

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