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Mucinous Adenocarcinoma of the Stomach Mimicking Submucosal Tumor, Report of a Case Noriya Uedo 1 , Hiroyasu Iishi 1 , Shingo Ishiguro 2 1Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases 2Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases Keyword: SMT様胃癌 , SMT , 粘液癌 , 胃癌 pp.1557-1561
Published Date 2003/10/25
DOI https://doi.org/10.11477/mf.1403100745
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 A 74-year-old man had a stomachache and underwent esophago-gastro-duodenoscopy (EGD) 28 months ago. A protruded tumor, 2 cm in size, with small shallow ulcers on its surface was found in the gastric body. The lesion increased in size and the ulcers enlarged during the observation period, so he was referred to our hospital for further examination and treatment. Barium meal study showed a broad based protruded tumor with an irregular ulcer on its surface. EGD revealed that the tumor was covered with normal gastric mucosa and had an irregular ulceration. There was no “IIc” component, which indicates intramucosal carcinoma, on the surface mucosa. Biopsy specimens that were taken from the ulceration contained no malignant cells but did contain mucin and inflammatory cells. We diagnosed it as a malignant submucosal tumor (SMT) and the patient underwent an operation. The tumor was 2.5 cm in size. It had invaded to the subserosa and was covered with normal gastric mucosa. Histologically, it consisted of rich mucin and a few cancer cells and it was diagnosed as mucinous adenocarcinoma of the stomach. There was no cancer tissue in the surface mucosa, which made it difficult to make a diagnosis by biopsy. Mucinous adenocarcinoma of the stomach sometimes appears as an SMT-like gastric carcinoma. It is important to make a diagnosis according to its endoscopic appearance and mucin in the biopsy specimen. Biopsy may be negative because of its normal surface mucosa and rich mucous component.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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