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Endoscopic Findings of Intramucosal Gastric Cancer with Metastasis Osamu Hosokawa 1 , Yasuharu Kaizaki 2 , Masakazu Hattori 1 , Kenji Dohden 1 , Hiroyuki Hayashi 1 , Tamon Miyanaga 1 , Kouji Ota 1 , Toshiyuki Okuda 1 , Mikio Tsukioka 3 1Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan 2Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan 3Tsukioka Clinic, Echizen, Japan Keyword: 胃粘膜内癌 , リンパ節転移 , 内視鏡所見 , 累積生存率 , 癌巣内潰瘍 pp.1141-1149
Published Date 2006/7/25
DOI https://doi.org/10.11477/mf.1403100624
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 Of 1,727 patients operated on for gastric intramucosal cancer in our hospital, 26 patients (1.5%) had lymph node metastasis. Female patients had more lymph node metastasis than male and the average age of node-positive patients was younger (51.4 years) than node-negative patients. The average diameter of cancers with lymph node metastasis was larger (4.3cm) and the histological type was undifferentiated in 20 patients. Ulceration was found in the cancerous lesions of 23 patients. There was significant relation between lymph node metastasis and invaded vessel. Lymph node metastasis was found frequently in patients with undifferentiated-type cancer with ulceration more than 10mm in diameter. Contrary to conventional reports, we found lymph node metastasis in differentiated-type cancer less than 30mm in diameter, or differentiated-type cancer without ulceration in the cancerous lesion. Because both metastatic lymph nodes and metastatic foci in lymph nodes were small, only 15.4% of patients were operatively diagnosed as having positive lymph node metastasis. The cumulative ten-year survival rate by Kaplan-Meier method was estimated as 96.0% for 26 patients having intramucosal gastric cancer with lymph node metastasis. We judged that diameter more than 20mm, submucosal components and pale color lesion peculiar to undifferentiated-type cancers were the important endoscopic findings for intramucosal gastric cancer with lymph node metastasis.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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