Inflammatory Myofibroblastic Tumor Arising From the Mesentery of the Small Intestine, Report of a Case Takashi Tashiro 1 , Tadashi Hasegawa 2 , Tadakazu Shimoda 1 1Division of Clinical Laboratory, National Cancer Center Hospital 2Division of Pathology, National Cancer Center Research Institute Keyword: 炎症性筋線維芽細胞性腫瘍 , GIST , 腸間膜 , 鑑別診断 , 小腸 pp.712-716
Published Date 2004/4/24
DOI https://doi.org/10.11477/mf.1403100513
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 During on operation for right renal carcinoma2years ago, a67-year-old man was found by chance to have intraabdominal masses. Small intestinal resection was performed because it was unclear whether the masses originated from the mucosa or mesentery of the small intestine and it could not be definitely denied that, macroscopically, the mass were mesenteric sarcoma. There were three submucosal tumors, solid and whitish colored, protruding into the serosa side continuously from the intestinal wall. On the cut surface, some lobulated nodules were noted. The tumors composed of fibroblastic cell proliferation were mainly located in the adipose tissue of the mesentery with a variable degree of collagen fibers, slightly edematous stroma, and inflammatory cells that included plasma cells, lymphocytes, and eosinophils. Blood vessels were conspicuous throughout the tumor. At the periphery, the tumor was not clearly demarcated and the tumor cells focally infiltrated into the mucosa and muscularis propria of the small intestine. Immunohistochemically, the tumor cells were positive for vimentin. The characteristic macro and microscopic findings led us to a diagnosis of inflammatory myofibroblastic tumor(IMT). IMT sometimes arises from the mesentery of the small intestine and it is necessary to differentiate it from gastrointestinal stromal tumor and mesenteric desmoid.

 1) Division of Clinical Laboratory, National Cancer Center Hospital, Tokyo

 2) Division of Pathology, National Cancer Center Research Institute, Tokyo

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