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Inflammatory Myofibroblastic Tumor Accompanied with a Developed Form of Behҫet's Disease, Report of a Case Ryu Sato 1 , Tomoyuki Ohta 1 , Masanori Murakami 1 1Department of Gastroenterology, Asahikawa Kosei General Hospital Keyword: Behҫet病 , IMT pp.115-120
Published Date 2004/1/25
DOI https://doi.org/10.11477/mf.1403100422
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 A 65-year-old woman, who had been treated for ocular Behҫet's disease since 1997, visited our unit, without any complaint, for intestinal screening in March, 2002. Colonoscopic examination showed a subpedunculated tumor measuring 20 mm in size covered with white coating on the ileocecal valve. Ulcer scars and small erosions were also seen in the terminal ileum. Barium enema study revealed the same polypoid lesion and inflammation in the ileocecum. Although the tumor was diagnosed as an inflammatory polyp according to the above findings, since it could not be ruled out as a malignant epithelial tumor, ileocecal resection was performed in May, 2002. Histological examination showed that the tumor consisted of spindle-shaped cell proliferation with a scattering of nuclear mitosis, lymphocytes and plasma cell infiltration based on severe submucosal fibrosis. Additionally non-specific erosions or ulcer scars were noted in the terminal ileum. Immunohistochemical study revealed that the tumor was positive for vimentin, and cytokeratin, but negative for ALK. Finally this tumor was diagnosed as IMT with intermediate malignant potential developed from intestinal Behҫet's disease.

 1) Department of Gastroenterology, Asahikawa Kosei General Hospital, Asahikawa, Japan


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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