Crater-like Early Esophageal Cancer of Well-differentiated Squamous Cell Carcinoma Associated with Marked Lymphocytic Infiltration, Report of a Case Kayoko Shimizu 1 , Hideki Koga 1,2 , Takashi Yao 3 , Kazuhiro Yoshida 4 , Tomoari Kamada 1 , Hiroaki Kusunoki 1 , Masaharu Takeda 1 , Keisuke Honda 1 , Yoshito Sadahira 5 , Tsukasa Tsunoda 4 , Ken Haruma 1 1Division of Gastroenterology, Department of Medicine, Kawasaki Medical School 2Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University 3Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University 4Department of Gastrointestinal Surgery, Kawasaki Medical School 5Department of Pathology, Kawasaki Medical School Keyword: 陥凹型食道癌 , 高分化型扁平上皮癌 pp.835-843
Published Date 2006/4/25
DOI https://doi.org/10.11477/mf.1403100375
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A 50-year-old Japanese man was admitted to our hospital because of a positive fecal occult blood test result.

 Esophagoscopy revealed a crater-like, oval depressed lesion with an undulated surface in the lower thoracic esophagus. Around the depression, a narrow protrusion covered with normal mucosa was recognized. The lesion was unstained with iodine. An endoscopic diagnosis of esophageal cancer invading the submucosal layer was made. Surprisingly, a barium examination disclosed the wall rigidity of the lesion to be extremely mild despite an evident depression followed by a rim-like surrounding elevation. Based on these findings, an unusual esophageal neoplasm, such as a poorly differentiated squamous cell carcinoma was suspected.

 Macroscopic examination of the resected specimen disclosed a whitish oval depression measuring 13×8 mm in size. Microscopically, the tumor consisted of well differentiated squamous cell carcinoma, which was minimally invading the submucosal layer. Marked lymphocytic infiltration was also seen.

 In this paper, we describe in detail an endoscopically, radiologically and histopathologically interesting case of esophageal cancer.

Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.


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