Japanese

Good Responses to Chemotherapy for Patients with Advanced Gastric Cancer, Report of Two Cases Ayumu Goto 1 , Tadakazu Shimoda 2 1Division of Gastrointestinal Oncology, National Cancer Center Hospital 2Pathology of Clinical Laboratory Division, National Cancer Center Hospital Keyword: 進行胃癌 , 術前化学療法 , S-1単独療法 , CDDP+CPT-11併用療法 pp.1043-1049
Published Date 2005/6/25
DOI https://doi.org/10.11477/mf.1403100223
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First case ; a male at the age of 69, was found by endoscopy to have advanced gastric cancer. Endoscopy showed invasion to the esophagus. The patient also underwent staging laparoscopy and his cytology was positive. He received 3 cycles of chemotherapy as neo-adjuvant setting(S-1, an oral fluoropyrimidine)and, according to the response of the primary lesion, he underwent curative total gastorectomy. Pathological findings indicated a wide range of fibration caused by the vanishing of the tumor.

 Second case ; a male at the age of 58, was found to have advanced gastric cancer. Endoscpopic findings showed a widespread Type 5 lesion between the cardia and the antrum and CT showed severe lymph node swelling directly invading the head of the pancreas. He received 3 cycles of chemotherapy as neo-adjuvant setting(cisplatin with irinotecan, a combination treatment)and underwent gastorectomy after the good response for LN metastasis. Pathological findings indicated a wide range of fibration and necrosis caused by the vanishing of the tumor. The area of the vanishing tumor in response to the treatment extended to two thirds of the whole tumor.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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