Epidemiology and Clinical Statistics of Oropharyngeal and Hypopharyngeal Carcinoma Kunitoshi Yoshino 1 1Department of Otolaryngology, Head and Neck Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases Keyword: 中咽頭癌 , 下咽頭癌 , 疫学 , 多重癌 , 飲酒・喫煙 pp.1229-1238
Published Date 2005/8/25
DOI https://doi.org/10.11477/mf.1403100148
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The incidence of carcinoma of the oropharynx(OPC)and the hypopharynx(HPC)has been gradually increasing, although much less than that of the esophagus. According to data from Osaka Cancer Registry, the male age-standardized incidence rates per 100,000(The Japanese 1985 model population)of OPC and HPC are 1.9 and 1.1 respectively over the last three years(1999~2001). These figures are about six times higher than 35 years ago. Most histological types of OPC and HPC are squamous cell carcinoma and the major carcinogenic risk factors are evidently excessive drinking and smoking. Multiple primary malignancies arise in about 25 % of the patients with OPC and HPC, 82 % of which are in the esophagus(37 %), the head & neck, the stomach and the lung. This suggests that careful examination for multiple primary malignancies in the upper aerodigestive tract is essential, especially in high-risk patients. Cooperation between concerned medical staffs will become increasingly important.

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