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The Usefulness of Dynamic Computed Tomography Scanning in Predicting the Outcome of Acute Stroke Patients Kimihiko CHOKYU 1 , Takahisa MORI 1 , Hiromi UETA 2 , Yoshinori OHATA 2 , Koichiro SOGABE 2 , Koreaki MORI 1 1Department of Neurosurgery, Kochi Medical School 2Department of Neurosurgery, Nakamura City Hospital Keyword: ischemic stroke , dynamic CT , outcome pp.735-741
Published Date 1999/8/10
DOI https://doi.org/10.11477/mf.1436901764

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  • Abstract
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The aim of this study was to investigate whether brain dynamic computed tomography (CT) is useful inpredicting clinical outcome. Thirty patients suffering from cerebral ischemia in the territory of the middlecerebral artery (MCA) underwent dynamic CT scanning within 6 hours of stroke onset. Regions of in-terest (ROIs) were placed in the bilateral MCA territories and three parameters, peak value (PV), time topeak (TP), and PV divided by TP, were calculated from time-density curves (TDCs) on ROIs. After con-ventional treatment using pharmacological agents, the 30-day clinical outcome was evaluated on the Glas-gow outcome scale. To investigate the relationship between the disease-to-contralateral side ratio of eachparameter's value and 30-day clinical outcome, TDCs were classified into the following four types ; type 1,with TP ratio less than 1. 1 ; type 2, with TP ratio ranging from 1. 1 to 1.5 and PV/TP ratio more than0.75 ; type 3, with TP ratio ranging from 1. 1 to 1.5 and PV/TP ratio less than 0.75 ; and type 4, with TPratio more than 1.5 and PV/TP ratio less than 0.3. Clinical outcome in patients with type 1 or 2 TDC wasbetter than in patients with type 3 or 4 TDC (p< 0.01, Fisher's exact test). We can conclude that dynamicCT is a useful means for estimating the clinical prognosis of acute stroke patients after conventional treat-ment. Poor clinical outcome following conventional therapy is expected in patients with type 3 or 4 TDCin contrast to patients with type 1 or 2 TDC.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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