胃食道逆流症と機能性ディスペプシア

Gastroesophageal Reflux Disease and Functional Dyspepsia

Point

・胃食道逆流症は，文献や人によって定義が異なる．難治性の場合は，専門施設での精査が望ましい．

・機能性ディスペプシアには多数の病態が関わっている．初期治療に抵抗性の場合，治療に難渋することが多い．

・これらの疾患は，悪性腫瘍などの器質的疾患がないと判断してから，診断されるべきである．

　Gastroesophageal reflux disease（GERD）and functional dyspepsia are common gastrointestinal disorders. GERD primarily manifests as heartburn and regurgitation, whereas functional dyspepsia is diagnosed in the absence of a discernible organic disease, despite persistent epigastric discomfort. Both GERD and functional dyspepsia can substantially worsen the patient's quality of life, although they do not typically influence prognosis. It is crucial to consider organic diseases, such as malignancies, particularly in patients who present with high-risk factors, including advanced age and weight loss. Patients with stable general health who are amenable to regular follow-ups and invasive procedures, such as endoscopy, should be advised to seek care at specialized facilities. This is particularly relevant if the initial treatment regimen fails to alleviate symptoms. This approach ensures optimal patient care and effective symptom management.