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Corticospinal Tract Mapping by Calculating the Ratio of Subcortical to Cortical Stimulation Intensity:A Technical Note Ryo HIRUTA 1,2 , Masazumi FUJII 2 , Yuya FURUKAWA 1,2 , Tsuyoshi ICHIKAWA 1 , Kyouichi SUZUKI 1 , Yoichi WATANABE 1 , Mio NEMOTO 2 , Taku SATO 2 , Jun SAKUMA 2 , Kiyoshi SAITO 2 1Department of Neurosurgery, Fukushima Red Cross Hospital 2Department of Neurosurgery, Fukushima Medical University Keyword: subcortical mapping , motor evoked potential , corticospinal tract , glioblastoma , nitrous oxide pp.957-960
Published Date 2019/9/10
DOI https://doi.org/10.11477/mf.1436204054

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  • Abstract
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 OBJECTIVE:Motor evoked potentials(MEPs)have been developed and utilized as safe surgical procedures. A correlation between the threshold intensity of direct stimulation MEPs and the distance of the corticospinal tract(CST)has been already established. However, MEPs are affected by anesthesia and patient-related conditions. Here, we describe a unique technique to avoid these effects.

 METHOD:When tumors developed in proximity to the CST, the transcortical MEP monitoring was done by placing grid electrodes on the primary motor cortex continuously while direct subcortical MEP mapping was conducted with a monopolar probe. The ratios of the subcortical to the transcortical stimulation intensity were calculated. The point at which the ratios reached 50% was defined as the surgical excision limit.

 DISCUSSION:MEPs are affected by anesthesia, paralysis, body temperature, and other factors. By measuring the ratio of the cortical stimulation intensity instead of the absolute value of the white matter stimulation intensity, various affecting factors can be avoided, and more accurate monitoring can become possible.

 CONCLUSION:By calculating the ratio of subcortical to cortical stimulation intensity, the corticospinal tract mapping is less likely to be influenced by the stimulation condition or facility setup, and this warrants further investigation.


Copyright © 2019, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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